Some people, however, against changes and chooses to stay in their comfort zone; while, the others have hard effort to get variation in their life.
I prefer to place all or part of the main sentence at the end of the sentence. Like this:
While others have..., some people... This focuses on the reader's attention on the complexity, rather than the simplicity, in this way address the essay's topic.
To sum up, it is difficult to overcome from a good condition; therefore, we might brave to move forward for self actualization purposes.
This is the pattern for the concluding paragraph I suggest:
1. a 'conclusion' signal: In conclusion, ....etc,
2. a summary of the main points or a restatement of the thesis (in different words!)
3. a final comment, based on the information in the essay
The final comment can be:3.1. a warning or prediction (often using the first conditional: If ..., ... will ...)
3.2. a suggestion or recommendation (often using should or must)