southlab
Oct 5, 2024
Graduate / Personal statement - integrative systems biology PhD program Pitt University [2]
Hello, I am new to writing personal statements and this will be the first program I will be applying too - Thank you in advance!
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Bioinformatics and systems biology weren't initially part of my career goals until my third year of college. However, life sciences have always fascinated me, particularly molecular biology and astronomy. I was captivated by the vastness of stars and the minuteness of molecules like DNA, RNA, and proteins. My first encounter with the central dogma in high school amazed me, and I was determined to study the science behind it. Although my college didn't offer a molecular biology program, I enrolled in biochemistry, which gave me a solid foundation in the field.
As the eldest child, I often found myself mediating conflicts between my younger siblings. While this experience isn't directly comparable to research, I developed a knack for problem-solving and discussion. My brief experiences working in an ice cream shop, pharmacy, and medical lab made me realize that the industry environment didn't suit me. I longed for more intellectual challenges and less routine work. This realization led me to pursue academia.
During my third year, I co-founded a student scientific community called LSD, where my peers and I shared our passion for research. We began working on a research project, even funding it ourselves due to the lack of institutional support. Our lecturer, [name], supervised us, and though budget constraints led us to work on natural products and animal models, the project taught me how to think systematically and interpret results. I learned techniques like chromatography and handling rat models, and the connections I made shaped my future in research. Our manuscript is now under review at the International Journal for Vitamin and Nutrition Research.
My introduction to bioinformatics came through a faculty member in my program, and I was immediately drawn to the field. I found the idea of analyzing large datasets, like thousands of genes or proteins, far more compelling than studying a single gene in isolation. My interest deepened when I learned about systems biology and protein-protein interactions while working on downstream analysis of expression microarray data. This fascination grew as I joined a journal club affiliated with Zewail City, where I co-presented a paper on multi-omics data integration. Although bioinformatics wasn't part of my formal curriculum, I sought out courses and workshops to build my expertise. For example, I took an introductory bioinformatics course with Dr. [name], learning about databases like NCBI, performing multiple sequence alignments, and using BLAST. We explored fields such as genomics and metagenomics, and I'm now collaborating on potential research projects with faculty members. Since bioinformatics is still developing in Egypt and many resources are costly, I relied heavily on self-teaching through tutorials and videos. Applying these skills to real data, I consulted with faculty when I faced challenges, and this hands-on approach helped me secure research opportunities.One of these opportunities was an internship at [name], where I worked on 16S metagenomics data. Currently, I'm involved in three bioinformatics/cheminformatics projects, all either under review or nearing completion. In addition, I developed a strong foundation in R, learning packages like tidyverse for data manipulation and ggplot2 for visualization. I applied these tools in analyzing expression microarray and bulk RNA-seq data using packages like limma and DESeq2. During my internship with Prof. Ashok, I expanded these skills, performing bulk RNA-seq analysis and creating visualizations, some of which I've shared on my GitHub.
In Python, I've applied my skills to more technical tasks, including developing a molecular docking pipeline to automate key steps in virtual screening. I researched the workflow, implemented a Python script to streamline processes, and utilized Matplotlib and WordCloud for visualizations in various projects. These experiences in bioinformatics and systems biology have shaped my thinking, teaching me how to organize complex projects and refine my scientific writing. Systems biology is still relatively unknown in Egypt, but the Integrative Systems Biology program at the University of Pittsburgh offers a unique opportunity for me to deepen my expertise in this field and strengthen my weaknesses. I'm particularly interested in studying protein-protein interactions, in areas host-pathogen dynamics, and modeling entire biological systems. I also believe the more I delve into this field, the more I will grow more interests.
I believe that my academic background, research experience, and skills in programming and data analysis have prepared me to meet the challenges of your program. I am excited about the opportunity to contribute to the field of bioinformatics and systems biology through the ISB program at the University of Pittsburgh.
Hello, I am new to writing personal statements and this will be the first program I will be applying too - Thank you in advance!
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Bioinformatics and systems biology weren't initially part of my career goals until my third year of college. However, life sciences have always fascinated me, particularly molecular biology and astronomy. I was captivated by the vastness of stars and the minuteness of molecules like DNA, RNA, and proteins. My first encounter with the central dogma in high school amazed me, and I was determined to study the science behind it. Although my college didn't offer a molecular biology program, I enrolled in biochemistry, which gave me a solid foundation in the field.
As the eldest child, I often found myself mediating conflicts between my younger siblings. While this experience isn't directly comparable to research, I developed a knack for problem-solving and discussion. My brief experiences working in an ice cream shop, pharmacy, and medical lab made me realize that the industry environment didn't suit me. I longed for more intellectual challenges and less routine work. This realization led me to pursue academia.
During my third year, I co-founded a student scientific community called LSD, where my peers and I shared our passion for research. We began working on a research project, even funding it ourselves due to the lack of institutional support. Our lecturer, [name], supervised us, and though budget constraints led us to work on natural products and animal models, the project taught me how to think systematically and interpret results. I learned techniques like chromatography and handling rat models, and the connections I made shaped my future in research. Our manuscript is now under review at the International Journal for Vitamin and Nutrition Research.
My introduction to bioinformatics came through a faculty member in my program, and I was immediately drawn to the field. I found the idea of analyzing large datasets, like thousands of genes or proteins, far more compelling than studying a single gene in isolation. My interest deepened when I learned about systems biology and protein-protein interactions while working on downstream analysis of expression microarray data. This fascination grew as I joined a journal club affiliated with Zewail City, where I co-presented a paper on multi-omics data integration. Although bioinformatics wasn't part of my formal curriculum, I sought out courses and workshops to build my expertise. For example, I took an introductory bioinformatics course with Dr. [name], learning about databases like NCBI, performing multiple sequence alignments, and using BLAST. We explored fields such as genomics and metagenomics, and I'm now collaborating on potential research projects with faculty members. Since bioinformatics is still developing in Egypt and many resources are costly, I relied heavily on self-teaching through tutorials and videos. Applying these skills to real data, I consulted with faculty when I faced challenges, and this hands-on approach helped me secure research opportunities.One of these opportunities was an internship at [name], where I worked on 16S metagenomics data. Currently, I'm involved in three bioinformatics/cheminformatics projects, all either under review or nearing completion. In addition, I developed a strong foundation in R, learning packages like tidyverse for data manipulation and ggplot2 for visualization. I applied these tools in analyzing expression microarray and bulk RNA-seq data using packages like limma and DESeq2. During my internship with Prof. Ashok, I expanded these skills, performing bulk RNA-seq analysis and creating visualizations, some of which I've shared on my GitHub.
In Python, I've applied my skills to more technical tasks, including developing a molecular docking pipeline to automate key steps in virtual screening. I researched the workflow, implemented a Python script to streamline processes, and utilized Matplotlib and WordCloud for visualizations in various projects. These experiences in bioinformatics and systems biology have shaped my thinking, teaching me how to organize complex projects and refine my scientific writing. Systems biology is still relatively unknown in Egypt, but the Integrative Systems Biology program at the University of Pittsburgh offers a unique opportunity for me to deepen my expertise in this field and strengthen my weaknesses. I'm particularly interested in studying protein-protein interactions, in areas host-pathogen dynamics, and modeling entire biological systems. I also believe the more I delve into this field, the more I will grow more interests.
I believe that my academic background, research experience, and skills in programming and data analysis have prepared me to meet the challenges of your program. I am excited about the opportunity to contribute to the field of bioinformatics and systems biology through the ISB program at the University of Pittsburgh.
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