Book Reports / Hamlet Grade 12 essay - Poison [2]

I have to write an essay on the theme of poison within Hamlet and so far this is my thesis statement:
The young prince of Denmark is poisoned physically and spiritually by the unfortunate events that occur within Shakespeare's play Hamlet.
So basically I'd be proving that he was poisoned literally and figuratively - mind and body.
It needs work so any help would be awesome.
Thanks a lot