Mehdi XXX
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Email: Mehdi XXX
July 9, 2014
Prof. Dr. XXX
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Email: XXX
Dear Professor XXX
I am writing to apply for the visiting researcher position in your research group in XXX laboratory. I am PhD student of Biophysics at faculty of XXX University. I do research in computational systems biology lab in the department of XXX.
My thesis title is "XXX". My research focuses on the identifying pathways and genes which involved in disease progression in order to improve the accuracy of prognosis and discovering new drug target. High-throughput microarray data was used for gene interaction network construction. Several statistical techniques implemented for preprocessing of microarray data, XXX, XXX and XXX. Different classification methods have been included for generating metagenes, XXX which used XXX and XXX that take advantage of XXX property of biological networks.
My investigation revealed that expression pattern of signaling pathways specially protein phosphorylation was altered in XXX. Splicing phenomena in the extracellular and structural proteins have been observed widely in this transition. Surprisingly, this phenomena was not observed to this extent in the XXX. We observed that two groups of genes are also participated in the XXX stage that responsible for cell growth and differentiation such as XXX receptor. The next step in the research that is ongoing, consist of the variable integration which was obtained from the previous step and clinical information that is implemented using XXX modeling and inspection of constructed networks.
During the investigation of gene interaction network, I realized that it is necessary to use network inferring, data integration methods and different computational and mathematical techniques, which is your research and laboratory scope that you expanded and apply these in your literature. Therefore, I am eager to expand my scientific knowledge and skills in the research areas wherein your lab specializes and utilizing them in my research and also to attain your valuable expertise.
So, it is a huge opportunity for me if you comply with my nine-month visiting researcher position application in your lab. I have enclosed my resume for your review. Kindly please let me know if I can provide additional information in support of my application. Thank you for your time and consideration.
Sincerely,
Mehdi XXX
---
Email: Mehdi XXX
July 9, 2014
Prof. Dr. XXX
----
Email: XXX
Dear Professor XXX
I am writing to apply for the visiting researcher position in your research group in XXX laboratory. I am PhD student of Biophysics at faculty of XXX University. I do research in computational systems biology lab in the department of XXX.
My thesis title is "XXX". My research focuses on the identifying pathways and genes which involved in disease progression in order to improve the accuracy of prognosis and discovering new drug target. High-throughput microarray data was used for gene interaction network construction. Several statistical techniques implemented for preprocessing of microarray data, XXX, XXX and XXX. Different classification methods have been included for generating metagenes, XXX which used XXX and XXX that take advantage of XXX property of biological networks.
My investigation revealed that expression pattern of signaling pathways specially protein phosphorylation was altered in XXX. Splicing phenomena in the extracellular and structural proteins have been observed widely in this transition. Surprisingly, this phenomena was not observed to this extent in the XXX. We observed that two groups of genes are also participated in the XXX stage that responsible for cell growth and differentiation such as XXX receptor. The next step in the research that is ongoing, consist of the variable integration which was obtained from the previous step and clinical information that is implemented using XXX modeling and inspection of constructed networks.
During the investigation of gene interaction network, I realized that it is necessary to use network inferring, data integration methods and different computational and mathematical techniques, which is your research and laboratory scope that you expanded and apply these in your literature. Therefore, I am eager to expand my scientific knowledge and skills in the research areas wherein your lab specializes and utilizing them in my research and also to attain your valuable expertise.
So, it is a huge opportunity for me if you comply with my nine-month visiting researcher position application in your lab. I have enclosed my resume for your review. Kindly please let me know if I can provide additional information in support of my application. Thank you for your time and consideration.
Sincerely,
Mehdi XXX