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My interest in pharmaceutical sciences back to my years in high school, where I excelled in chemistry and biology. When I was a senior, I have volunteered in hospice care for patients with terminal cancer and realised that if highly effective targeted medicine could be developed to act directly against cancer cells, it could improve the quality of life and save these patients from cancer. It seemed only logical that I pursue a career in medicinal chemistry.
When I began my undergraduate career at Shenyang Pharmaceutical University, I had the opportunity to be exposed to the full range of pharmacy courses，all of which strengthened my determination to study in the field of pharmacy. After graduating, I obtained a Bachelor's degree in Environmental Science and a second degree in Traditional Chinese Medicine.
I have taken basic theoretical courses in organic chemistry, inorganic chemistry, physical chemistry and biochemistry. Furthermore, l have mastered the basic operations necessary for pharmacological experiments during my laboratory training, completed relevant laboratory courses and acquired basic skills in the synthesis of target compounds, such as recrystallisation, extraction and analytical spectroscopy.
During my professional studies, I have acquired basic theories, knowledge and skills in chemistry, biology, medicinal chemistry, microbiology and toxicology. I have received initial training in research methods and have initial competence in research, technology development, engineering design, production technology production management, environmental management and consultancy in pharmacy and related fields. I have become skilled in reading and translating relevant English literature and related materials in my field, understanding the latest research developments and writing reviews. In addition, I have acquired the ability to independently design and improve experiments based on available information, draw reasonable conclusions about experimental results, and present and reflect on them. Not only have I acquired a wealth of theoretical knowledge，but also I have also participated in a number of research projects：
One of these studies was on FAK inhibitors, a process that allowed me to acquire structure-based drug design skills. This included summarising and analysing existing compounds, designing the parent ring, testing the biological activity of different substituents and finally performing molecular docking studies. Another important study was on the interaction between norfloxacin and metformin. The most important inspiration for me from this study is that we should not only discover new drugs, but the discovery of other effects of old drugs and their potential side effects can guide the treatment of diseases, especially some chronic ones.
I was the project leader and team captain for both the medicinal chemistry laboratory internship and the running of the debate team.In those process, I learnt how to lead a group through our projects. Firstly, I need to assess whether I am capable of taking on the current project, and even if I find that I am not capable, it does not matter, I need to be a team member and work hard to learn the skills so that I can do better on the next project. Secondly, I need to schedule the time cycle of the project, coordinate our work, estimate the approximate funds to prevent wasting resources; clarify everyone's responsibilities and conduct weekly phase summaries to prevent delays in projects and learning. We have to consider various ways to solve the problems we encounter in our project research and in organising extra-curricular activities. Whether it works or not, it must be tried. But when we encounter technical difficulties that are beyond our abilities, unless we have the time and capability to do so, ask for assistance from professors and senior students if necessary. Finally, mentality is more important than ability. Unexpected failures are common in pharmacy experiments and we will have the motivation to continue research only if we do not let difficulties get us down.
The MSc in medicinal chemistry involves learning the fundamentals of drug design and development, synthesising drugs containing new functional groups, exploring the effects of conception on the live image of a drug and examining the physiological activity of target compounds. Fortunately, my theoretical and practical knowledge of organic and medicinal chemistry provides the foundation for the synthesis of compounds in the laboratory, and my knowledge of toxicology, biology and molecular biology helps me to study peptide and protein chemistry. All of these will help me to complete my postgraduate studies and research on inhibitors related to tumour development.
After my undergraduate studies and trying out various areas of research, I have found that I am more interested in medicinal chemistry, especially structure-based synthesis of targeted antitumour drugs. A few months ago I learned that a class of fak kinase inhibitors is expected to hit the market, suggesting that compounds that act on signal transduction molecules could hold great promise for cancer patients. By checking the university's website, I found out that there are professors working on certain signal transduction proteins related to the regulation of metabolism and carcinogenesis. In addition, I have already contacted Prof. Trond Ulven, who is very interested in my chosen research direction of eEF2K and AMPK inhibitors and is willing to support this project.
Of course, my plans following completion of my current studies are to move directly into graduate work toward my master's in science. After I earn my master's degree, I intend to start work on my Ph.D. at the University of Copenhagen. Later I would like to work in the area of research and development for a high-impact pharmaceutical company. It is in R & D that I believe I can make the greatest contribution, utilizing my theoretical background and creativity as a scientist.
I am highly aware of the superb reputation of your school, and my conversations with several of your alumni have served to deepen my interest in attending. I know that, in addition to your excellent faculty, your laboratory equipment are among the best in the state. I hope you will give me the privilege of continuing my studies at your fine institution.
Holt Educational Consultant - / 12,672 4113
When you write a personal statement, do not focus on your academic background and community leadership. The personal statement, if given to you without a prompt instruction, should detail the development of your interest in ths masters course based on your professional exposure to the field over several years. Do not repeat the course coverage or syllabus details either. The reviewer already knows that information and does not need to be lectured about it. What you can do is take paragraphs 2,3,and 8, incorporating those into a proper personal statement that leads up to the realization of your need to pursue higher academic training based on your career needs. Talk about how you were inspired to attend this course at this university based on your personal academic requirements and (if needed) personal development.